The final proposed mechanism of RBC vasodilation while in the presence of nitrite will be the reduction of nitrite to NO by Hb. Brooks to start with researched the nitrite Hb conversation in 1937 which perform was afterwards prolonged by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to type metHb and NO (Broo